King's College - Biology Department

Dr. Chad Welsh, Ph.D.
Office: P309
Phone Number: 570-208-5900 Ext. 5363
Email: ChadWelsh@kings.edu

EDUCATION

University of Louisville, Louisville, Kentucky, 1998-2003
Ph.D. in Microbiology and Immunology, 2003,
Area of Specialization: Host- Pathogen interactions

Middle Tennessee State University, Murfreesboro, Tennessee, 1991-1998
M.S. in Biological Sciences, concentration in Microbiology
B.S. in Biological Sciences, major in Microbiology

RESEARCH INTERESTS

Host intracellular signaling response to pathogens.
Adaptation of bacterial pathogens from protozoan reservoir to human host.
Pathogen alteration of host responses

PUBLICATIONS

1: Welsh CT, GB Pevow, P Stathopoulou, DF Kinane, DS Darling. Cloning Oral Bacterial Antigens by Genomic Expression Libraries. (submitted to Journal of Dental Research)

2: Welsh CT, Summersgill JT, Miller RD. Legionella pneumophila Stimulates the c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase and p38 Pathways in the Activation of Caspase-3 in Monocyte-Derived Macrophages. (submitted to Microbial Pathogenesis)

3: Welsh CT, Summersgill JT, Miller RD. Increases in c-Jun N-terminal kinase/stress-activated protein kinase and p38 activity in monocyte-derived macrophages following the uptake of Legionella pneumophila. Infect Immun. 2004 Mar;72(3):1512-8.

4: Welsh, CT. Death of a Host: Virulence Associated Induction of Apoptosis by Legionella pneumophila in Monocyte-Derived Macrophages via the SAPK/JNK and p38 Signaling Pathways (Dissertation). University of Louisville. Louisville, KY.

5: Desai R, Welsh C, Summy M, Farone M, Newsome AL. The potential of in situ hybridization and an immunogold assay to identify Legionella associations with other microorganisms. J Microbiol Methods. 1999 Aug;37(2):155-64.

6: Welsh CT. Development of an Identification System for Legionella Using an Immunogold Antibody Labeled Assay (Thesis). Middle Tennessee State University,
Murfreesboro, TN. 1998.

SELECTED SEMINAR/POSTER PRESENTATIONS

"A Genomic Protein Expression Library to Identify Oral Bacterial Antigens" American Association for Dental Research General Meeting. New Orleans, LA. 2007.

"Identification of Oral Bacterial Protein Antigens Through the Use of a Whole Genome Protein Expression Library." Research Louisville 2006. University of Louisville, KY, 2006.

"Death of a Host: Virulence Associated Induction of Apoptosis by Legionella pneumophila in Monocyte-Derived Macrophages via the SAPK/JNK and p38 Signaling Pathways : (Dissertation Defense)" University of Louisville, Louisville, KY, 2003

"Altered Signaling in the Mitogen Activated Protein Kinase (MAPK) Cascades Following Uptake of Legionella pneumophila by Monocyte-Derived Macrophages (Poster)" American Society of Microbiology General Meeting. Washington DC. 2003

"Signaling in the Macrophage Mitogen Activated Protein Kinase (MAPK) Cascades Following Uptake of Legionella pneumophila (Poster)" American Society of Microbiology General Meeting. Salt Lake City, UT. 2002

"Alterations in the Monocyte MAPK Cascade Following Uptake of Legionella pneumophila (Poster)" Interscience Conference on Antimicrobial Agents and
Chemotherapy (ICAAC). Chicago, IL. 2002.

8th International Conference on the Biology and Pathogenicity of Free-Living Amoebae. MTSU, Murfreesboro, Tennessee 1998

"Evaluation of Ribosomal Protein L9 Sequence conservation within Subphylum Vertebrata (Seminar)" Tennessee Academy of Science Annual Meeting. 1997.

AFFILIATIONS
American Society for Microbiology 1997-Present
Tennessee Academy of Science 1996-1998

AWARDS/HONORS

2006 Honorable Mention, Research Louisville 2006 Post-Doctoral Research Associates Section.